Substrate: Serine/threonine-protein kinase PAK 1 (Ser/Thr protein kinase family)
Seq-ID: O88643 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-19486   ARHG7_HUMAN
MINT-19793   NCK1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
ATP binding		 focal adhesion,
axon,
growth cone		 dendrite development,
protein amino acid phosphorylation,
neuromuscular junction development,
receptor clustering
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 144 KKTSNSKKYMSFTDKSAEDYN - 14500679
LTP
0.52
 - -
0.65
 1F3M 86.89%
S 199 VIAPRPEHTKSVYTRSVIEPL - 14500679
LTP
0.80
 - -
0.68
 --
S 204 PEHTKSVYTRSVIEPLPVTPT - 14500679
LTP
0.38
 - -
0.69
 --
T 212 TRSVIEPLPVTPTRDVATSPI CDK5 11604394
LTP
0.13
 MOD_CDK_SPxK_1
 - -
0.68
 --
T 212 TRSVIEPLPVTPTRDVATSPI CDK1 12176333
LTP
0.13
 MOD_CDK_SPxK_1
 - -
0.68
 --
T 212 TRSVIEPLPVTPTRDVATSPI - 17114649
HTP
0.13
 MOD_CDK_SPxK_1
 - -
0.68
 --
S 220 PVTPTRDVATSPISPTENNTT - 15345747
HTP
0.36
 - -
0.89
 --
S 223 PTRDVATSPISPTENNTTPPD - 17114649
HTP
0.09
 - -
0.89
 --
T 225 RDVATSPISPTENNTTPPDAL - 17114649
HTP
0.14
 - -
0.89
 --
T 423 QITPEQSKRSTMVGTPYWMAP - 12719581
LTP
1.00
 - S_TKc
0.36
 --
T 423 QITPEQSKRSTMVGTPYWMAP - 17242355
HTP
1.00
 - S_TKc
0.36
 --
T 423 QITPEQSKRSTMVGTPYWMAP - 14500679
LTP
1.00
 - S_TKc
0.36
 --

Substrate: Serine/threonine-protein kinase PAK 1 (Ser/Thr protein kinase family)
Seq-ID: P35465 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein kinase binding,
ATP binding,
MAP kinase kinase kinase activity		 membrane fraction,
intercalated disc,
dendrite,
cytosol,
nuclear membrane,
axon,
Z disc		 response to hypoxia,
positive regulation of JUN kinase activity,
neuron projection morphogenesis,
protein amino acid autophosphorylation,
regulation of actin cytoskeleton organization,
cellular response to insulin stimulus,
cellular response to stress,
small GTPase mediated signal transduction,
intracellular protein kinase cascade
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 144 KKTSNSQKYMSFTDKSAEDYN - 16396499
HTP
0.62
 - -
0.68
 1F3M 86.89%

Substrate: Serine/threonine-protein kinase PAK 1 (Ser/Thr protein kinase family)
Seq-ID: Q13153 [Homo sapiens]
Download:fasta csv
Interaction Network(s): NetworKIN
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-14030   CDC42_HUMAN
MINT-61476   NCK1_HUMAN
MINT-1771821   CD11B_HUMAN
MINT-1953519   GIT1_HUMAN
MINT-1953555   GIT2_HUMAN
MINT-3389399   RAF1_HUMAN
MINT-6541935   SRC8_HUMAN
MINT-7211888   SH3K1_HUMAN
MINT-7212697   ARHG7_HUMAN
MINT-7217644   RAC1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein serine/threonine kinase activity,
collagen binding,
ATP binding		 focal adhesion,
cytosol,
Golgi apparatus		 ER-nucleus signaling pathway,
apoptosis,
positive regulation of JUN kinase activity,
protein amino acid autophosphorylation,
cytoskeleton organization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 212 TRSVIEPLPVTPTRDVATSPI CDK_group 11604394
LTP
0.12
 MOD_CDK_SPxK_1
 - -
0.68
 --
T 212 TRSVIEPLPVTPTRDVATSPI MAPK1 15542607
LTP
0.12
 MOD_CDK_SPxK_1
 - -
0.68
 --
T 212 TRSVIEPLPVTPTRDVATSPI - 16964243
HTP
0.12
 MOD_CDK_SPxK_1
 - -
0.68
 --
T 212 TRSVIEPLPVTPTRDVATSPI - 18669648
HTP
0.12
 MOD_CDK_SPxK_1
 - -
0.68
 --
S 220 PVTPTRDVATSPISPTENNTT - 18669648
HTP
0.50
 - -
0.89
 --
S 223 PTRDVATSPISPTENNTTPPD - 18669648
HTP
0.07
 - -
0.89
 --
T 230 SPISPTENNTTPPDALTRNTE - 18669648
HTP
0.16
 - -
0.91
 --
T 423 QITPEQSKRSTMVGTPYWMAP PDK-1 10995762
LTP
1.00
 - S_TKc
0.37
 3FXZ 72.60%
T 423 QITPEQSKRSTMVGTPYWMAP - 11134074
LTP
1.00
 - S_TKc
0.37
 3FXZ 72.60%

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